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Understanding the Tissue Transglutaminase IgA Test

A tissue transglutaminase IgA test is an effective way of diagnosing celiac disease. The test is a simple blood test to check the amount of this immunoglobulin or antibody in the blood. If there is a higher amount of  tissue transglutaminase antibody than the normal range, it indicates the possibility of celiac disease. 

Celiac disease  is an autoimmune disorder that makes the immune system think that gluten is a foreign invader. Due to this, it produces a higher amount of antibodies to fight gluten. These antibodies attack tissue transglutaminase, which is an enzyme present in the intestines and is responsible for the cell healing process.

If you suspect you have celiac disease with possible symptoms, book a tissue transglutaminase IgA test at our laboratory. At Agilus Diagnostics, we offer a comprehensive Celiac Screen test package that includes Tissue transglutaminase antibody (tTG) test. 

However, before undergoing the test, you must understand the test in detail. In this blog post, we will discuss in detail the tissue transglutaminase IgA test.

How Is The Tissue Transglutaminase IgA Test Done?

The person has to have a gluten-containing diet before undergoing the tissue transglutaminase IgA test to get accurate results. Even if you are suffering from celiac disease, a lack of gluten in your body will not give accurate results. 

The physician will recommend you get a tTg-IgA test before you stop eating a gluten diet. Except for this, no other preparation is needed . However, you need to inform your doctor of the medications you are taking on a regular basis along with the complete medical history.  

A blood sample is taken to conduct the tissue transglutaminase IgA test. The lab specialist will use a needle to prick and draw a certain amount of blood out of your vein. The blood will be then tested for anti-tissue transglutaminase antibodies. If it is found that your blood contains higher levels of antibodies, it will give a confirmation of the celiac disease condition.

When is the tTG-IgA Test Done?

An anti tTG iga test is recommended or advised by the doctor when you have possible symptoms of celiac disease. However, the symptoms will vary from person to person. Not every individual will show similar symptoms. If you have celiac disease, here is the list of signs and symptoms you may face;

  • Bloating
  • Constipation
  • Unending nausea
  • Stomach pain
  • Inability to digest milk
  • Diarrhoea
  • Gaseous feeling
  • Vomiting
  • Watery stool

However, it is noticed that the above symptoms are prevalent in children. They may show other symptoms, such as skin rashes and tooth enamel problems. Children who are suffering from celiac disease will usually face trouble growing with age because of the inability to absorb nutrients. Hence, they will face delays in height growth and puberty. Moreover, they will have slower grasping power and metabolism. 

It is recommended to look for the potential symptoms before consulting the doctor. When you notice a few symptoms, it does not necessarily mean you have celiac disease. You may be suffering from other medical conditions. If you notice any of the above symptoms, book a TTG blood test at our diagnostic centre, which is nearest to your location. 

When Is the tTG Level High?

When you have more than 11 U/mL tTG in your blood, which is the highest level, this means that you have celiac disease. In this case, an immediate diagnosis step has to be taken. You must be aware of the normal range of tTG in the human body.

When the antibody level is lower or equal to 3 U/mL, it means that it is at a normal or average level. And when it ranges between 4 to 10 U/mL, it is considered a weak positive range. But, when it is found to be more than or equal to 11 U/mL, it means that your body is more likely to have celiac disease.  So, the TTG test normal range is less than 4.0 U/ml.

Tissue Transglutaminase IgA Test Results

The test results will vary based on the patient’s age, genetics, medical history, and other factors. Therefore,it is better to consult a doctor before undergoing the tTG blood test.

If your test shows <4.0 U/mL, this means negative, and if it shows between 4.0 to 10.0 U/mL, it means weak positive, and >10.0 U/mL means positive. These values are applied to every age group. When it shows positive for tissue transglutaminase IgA antibodies, this is consistent with a diagnosis of celiac disease .

Getting the lab tests done from our lab will give you an accurate result of the Tissue Transglutaminase IgA range and the possibility of celiac disease. So, when you have celiac disease or other related disorders, you will produce high levels of antibodies. However, the tests might not be effective in the case of children with this disease. 

Therefore, you need to consult the best laboratory. At our laboratory, we promise to give you accurate results. You can book our tissue transglutaminase IgA and serum test online and request a home sample collection. We will deliver the reports as quickly as possible. 

Who Has To Undergo The Tissue Transglutaminase IgA Test?

Here are the individuals who have to undergo the Tissue Transglutaminase IgA Test;

  • An individual who shows all the symptoms of celiac disease, for example, bloating, chronic diarrhoea, abdomen pain, weight loss, and anaemia. 
  • When the infant is not growing, or growth is delayed compared to the normal rate.
  • When you find an infant irritable for a long time.
  • An individual who has a family history of celiac disease.
  • Apart from the above, patients who are undergoing treatment for celiac disease must have regular tests as recommended by the doctor. 

Final Thoughts

The tissue Transglutaminase IgA Test is a must when you have potential symptoms of celiac disease. When the celiac disease diagnosis is delayed, it will lead to reduced well-being and long-term effects. This will further increase the use of medicines and expensive healthcare services. This is why we recommend you make an early diagnosis before it is too late. You can book an online test for tissue transglutaminase (IgA) at our nearest diagnostic centre and get the right results so that you can take further treatment action. 

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