Chromogranin A, Serum

What is Chromogranin A, test?

The Chromogranin A test is a blood test that measures the levels of a protein called chromogranin A. Chromogranin A is produced by neuroendocrine cells found in various organs, so elevated levels can help in the diagnosis, monitoring, and management of neuroendocrine tumors. The test can also be used to assess disease progression, monitor treatment response, and detect recurrence after treatment.

Why consider Chromogranin A, test?

• To evaluate suspected neuroendocrine tumors based on symptoms or imaging and to establish a baseline before therapy.
• For serial monitoring in confirmed neuroendocrine tumors to assess disease burden, treatment effectiveness, and relapse during follow‑up.

Who should get this Chromogranin A, test?

• Individuals with features suggestive of neuroendocrine tumors (e.g., flushing, diarrhea, wheeze/bronchospasm, abdominal pain, unexplained weight loss).
• Patients with imaging/biopsy suspicious for neuroendocrine tumors or with a known neuroendocrine tumor who need baseline and periodic monitoring.

More Information about Chromogranin A, test

Chromogranin A is a protein released by neuroendocrine cells. A neuroendocrine tumor (NET) is a rare type of cancer that starts in neuroendocrine cells. There are several types of neuroendocrine tumors with symptoms that are easy to mistake for other less serious conditions. The characteristics of NETs — including how aggressive (fast-growing) they are, the symptoms they cause and what treatments work best — vary significantly based on the tumor.

OTHER NAMES: CgA; Chromogranin‑A, Neuroendocrine tumor marker, Chromogranin A, Serum Chromogranin A (S‑CgA)