Autoimmune Encephalitis Panel-2 With Dppx, Serum

What is Autoimmune Encephalitis Panel-2 With DPPX, Serum test?

Autoimmune encephalitis (AE) is a group of neurological disorders where the immune system mistakenly attacks the brain.

The Autoimmune Encephalitis Panel-2 With DPPX, Serum is a comprehensive diagnostic test performed on cerebrospinal fluid (CSF) to detect autoantibodies associated with autoimmune encephalitis (AE) These antibodies target brain proteins and are linked with inflammation of the brain that can cause seizures, psychiatric symptoms, memory loss, movement disorders, and altered consciousness. DPPX is a protein found on the surface of neurons, involved in regulating neuronal excitability. DPPX-6 antibody test detects antibodies against DPPX (dipeptidyl-peptidase-like protein 6) in the cerebrospinal fluid (CSF).

Parameters Covered - NMDA, AMPA (GLUR1 + GLUR2), GABA B RECEPTOR, VGKC (LGI1,- CASPR2), DPPX.

Why consider Autoimmune Encephalitis Panel-2 With DPPX, Serum test?

Autoimmune Encephalitis Panel-2 With DPPX, serum test is considered for

• To diagnose autoimmune encephalitis in patients with neurological or psychiatric symptoms.
• To differentiate autoimmune causes from infections or primary psychiatric disorders.
• To guide treatment decisions, such as immunotherapy.
• To identify paraneoplastic syndromes associated with underlying cancers.
• To help monitor disease progression and response to therapy.

Who should get tested for Autoimmune Encephalitis Panel-2 With DPPX, Serum test?

Autoimmune Encephalitis Panel-2 With DPPX, serum test is recommended for

• Patients with sudden or unexplained neurological symptoms such as seizures, memory loss, confusion, or behavioral changes.
• Patients with psychiatric symptoms like psychosis or mood disturbances that do not respond to standard treatment.
• Patients suspected of having a paraneoplastic neurological syndrome.
• Individuals with abnormal movements or altered consciousness of unclear cause.

More Information

Other Names: Autoimmune Encephalopathy Panel, Encephalitis Panel, Autoimmune Encephalitis Panel, Autoimmune Encephalitis antibody panel, Comprehensive Autoimmune Encephalitis Panel

Encephalitis is inflammation of the brain. It can be caused by viral or bacterial infections, or by immune cells mistakenly attacking the brain. Viruses that can lead to encephalitis can be spread by insects such as mosquitos and ticks.

When inflammation is caused by an infection in the brain, it's known as infectious encephalitis. And when it's caused by the immune system attacking the brain, it's known as autoimmune encephalitis. Sometimes there is no known cause.