HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING

The HLA Total test assesses compatibility between donor and recipient using various methods, including flow cytometry, complement-dependent cytotoxicity (CDC), and mixed lymphocyte culture (CMX). It is used to optimize donor selection for organ and stem cell transplants. The comprehensive analysis helps reduce the risk of rejection.

Also known asHla Total (hla Duo+cdc-cmx+ Flow Cmx) Hla Total (hla Duo+cdc-cmx+ Flow Cmx)

Available via

Home Collection, Lab Visit

Contains

30 parameters

Earliest reports in

Same Day

Test details

HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING Package in Bengaluru Overview

What is HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?

  • HLA Duo ABDR & CDC and Flow Cytometry Cross is a bundled pre-transplant compatibility workup combining donor–recipient HLA typing at A, B, and DR loci along with CDC crossmatch and flow crossmatch.
  • ABDR refers to genotyping/antigen typing at HLA‑A, HLA‑B, and HLA‑DRB1. CDC crossmatch detects complement‑fixing antibodies and flow crossmatch detects lower‑titer IgG on T/B cells.

Why consider HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?

This panel is recommended in below clinical conditions -

  • Detects different antibody risks
  • Guides peri‑transplant management
  • Orthogonal confirmation

Who should get this HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?

  • All solid‑organ transplant candidates and intended living donors during compatibility workup, particularly kidney recipients, where crossmatch status strongly correlates with rejection and graft survival.
  • Sensitized recipients with prior transplants, transfusions, or pregnancies, where detecting any level of donor‑specific antibody is critical to planning or deferring transplantation.

More Information about HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test

Human leukocyte antigens are of three main types. Class I HLA antigens include HLA-A, B, and C molecules; class II, which includes HLA-DR, -DQ, and -DP loci, are on antigen-presenting cells; and class III contains genes for proteins that have immune functionality.

HLA class I typing is used to identify HLA-matched platelets for alloimmunized refractory patients and identify presence of HLA antigens associated with a number of diseases or as drug hypersensitivity markers class I HLA antigens include A, B, and C loci.

OTHER NAMES: HLA Typing, Human Leukocyte Antigen, HLA Typing High resolution, HLA Typing for donor & recipient, HLA Typing by NGS, Solid Organ Transplantation, Kidney Transplant, Stem cell transplant, Bone marrow transplant, Crossmatch, HLA with crossmatch, HLA & crossmatch test

Preparations

No special preparations needed

Test included
HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING includes 30 parameters

  • B- Cell Crossmatch

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • Hla-a
  • Hla-b
  • Hla-dr

  • T-cell Crossmatch

  • B-cell Crossmatch

  • T & B Cell Crossmatch

  • T-cell Crossmatch

  • T & B Cell Crossmatch

Test code

SP3092

Specimen vol. and vacutainer information
SpecimenVacutainerVolume
Donor HeparinGreen Vacutainer
Donor Whole BloodLavender Vacutainer
Edta Whole BloodLavender Vacutainer2 ML
Heparin Whole BloodGreen Vacutainer3 ML
Receipient SerumYellow Vacutainer
SerumYellow Vacutainer3 ML

Specimen stability information

Edta Whole Blood, Heparin Whole Blood, Serum

Collection instructions

All Days

Specimen rejection criteria

Test run frequency

'

Turn around time

Same Day

Performing locations

Department

  • Hla Coe
  • Hla Serology

CPT and Loinc codes

HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING

42000