HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING
The HLA Total test assesses compatibility between donor and recipient using various methods, including flow cytometry, complement-dependent cytotoxicity (CDC), and mixed lymphocyte culture (CMX). It is used to optimize donor selection for organ and stem cell transplants. The comprehensive analysis helps reduce the risk of rejection.
HLA DUO ABDR & CDC & FLOWCYTOMETRY CROSSMATCHING Package in Vadodara Overview
What is HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?
- HLA Duo ABDR & CDC and Flow Cytometry Cross is a bundled pre-transplant compatibility workup combining donor–recipient HLA typing at A, B, and DR loci along with CDC crossmatch and flow crossmatch.
- ABDR refers to genotyping/antigen typing at HLA‑A, HLA‑B, and HLA‑DRB1. CDC crossmatch detects complement‑fixing antibodies and flow crossmatch detects lower‑titer IgG on T/B cells.
Why consider HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?
This panel is recommended in below clinical conditions -
- Detects different antibody risks
- Guides peri‑transplant management
- Orthogonal confirmation
Who should get this HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test?
- All solid‑organ transplant candidates and intended living donors during compatibility workup, particularly kidney recipients, where crossmatch status strongly correlates with rejection and graft survival.
- Sensitized recipients with prior transplants, transfusions, or pregnancies, where detecting any level of donor‑specific antibody is critical to planning or deferring transplantation.
More Information about HLA DUO A,B,DR Typing with CDC & flow cytometry Crossmatch test
Human leukocyte antigens are of three main types. Class I HLA antigens include HLA-A, B, and C molecules; class II, which includes HLA-DR, -DQ, and -DP loci, are on antigen-presenting cells; and class III contains genes for proteins that have immune functionality.
HLA class I typing is used to identify HLA-matched platelets for alloimmunized refractory patients and identify presence of HLA antigens associated with a number of diseases or as drug hypersensitivity markers class I HLA antigens include A, B, and C loci.
OTHER NAMES: HLA Typing, Human Leukocyte Antigen, HLA Typing High resolution, HLA Typing for donor & recipient, HLA Typing by NGS, Solid Organ Transplantation, Kidney Transplant, Stem cell transplant, Bone marrow transplant, Crossmatch, HLA with crossmatch, HLA & crossmatch test
No special preparations needed
- B- Cell Crossmatch
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- Hla-a
- Hla-b
- Hla-dr
- T-cell Crossmatch
- B-cell Crossmatch
- T & B Cell Crossmatch
- T-cell Crossmatch
- T & B Cell Crossmatch
Test code
SP3092
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Donor Heparin | Green Vacutainer | |
| Donor Whole Blood | Lavender Vacutainer | |
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
| Heparin Whole Blood | Green Vacutainer | 3 ML |
| Receipient Serum | Yellow Vacutainer | |
| Serum | Yellow Vacutainer | 3 ML |
Specimen stability information
Edta Whole Blood, Heparin Whole Blood, Serum
Collection instructions
All Days
Specimen rejection criteria
Test run frequency
'
Turn around time
Same Day
Performing locations
Department
- Hla Coe
- Hla Serology
CPT and Loinc codes
Package price
₹42000
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₹42000