G6PD, Quantitative

The G6PD Quantitative Blood test is commonly performed in newborns as part of routine screening to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency. This inherited enzyme disorder can lead to hemolytic anemia, especially when exposed to certain medications, foods, or infections. Early detection in newborns is important to prevent complications like severe jaundice or red blood cell breakdown. The test helps identify at-risk infants so that proper precautions can be taken from birth.

Why consider G6PD Quantitative Blood test?

The quantitative G-6-PD test measures the level of this enzyme in the blood and is essential for diagnosing:

• G-6-PD Deficiency: A genetic condition that can cause hemolytic anemia, especially after exposure to certain triggers, such as infections, medications (like sulfa drugs), or foods (such as fava beans).
• Hemolytic Anemia: Identifies the underlying cause of unexplained anemia, particularly in men or individuals with a family history of G-6-PD deficiency.

Who should get G6PD Quantitative Blood test done?

• Newborns or infants, as G-6-PD deficiency can cause jaundice.
• Individuals of certain ethnic backgrounds (e.g., those of African, Middle Eastern, or Mediterranean descent) who are at higher risk.
• People with unexplained hemolytic anemia, particularly after exposure to triggers.

More Information about G6PD Quantitative Blood test

G-6-PD deficiency is an X-linked genetic disorder, more common in males. The test measures the level of G-6-PD enzyme activity, and low levels are indicative of a deficiency. Management involves avoiding triggers that may cause red blood cell destruction.

Other Names: Glucose-6-Phosphate Dehydrogenase Assay, G6PD Enzyme Activity Test, G6PD Deficiency Test