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Mismatch Repair Gene (MMR)

This panel tests for mutations in mismatch repair genes, which are critical in preventing DNA errors. It is particularly useful in the diagnosis of Lynch syndrome and related cancers.

Also known asmismatch repair gene ihcmmr protein testinglynch syndrome screeningdna repair ihc

Available via

Home Collection, Lab Visit

Contains

15 parameters

Earliest reports in

6 Working Days

Test details

Mismatch Repair Gene (MMR) Test in Chandigarh Overview

Preparations

No special preparations needed

Test included
Mismatch Repair Gene (MMR) includes 15 parameters

  • Specimen
  • Request Letter
  • Additional Communication
  • Mlh1

  • Request Letter
  • Additional Communication
  • Msh2

  • Request Letter
  • Additional Communication
  • Msh6

  • Request Letter
  • Additional Communication
  • Pms2
  • Diagnosis
  • Comments
Frequently Asked Questions

This test analyzes tissue samples to detect the expression of mismatch repair (MMR) proteins using immunohistochemistry (IHC). MMR proteins repair DNA errors during cell division, and their loss indicates microsatellite instability (MSI), commonly associated with Lynch syndrome and colorectal cancer.

This test is recommended for:

  • Patients diagnosed with colorectal or endometrial cancer.
  • Individuals with a family history of Lynch syndrome.
  • Those with suspected hereditary cancer syndromes.

A tissue biopsy is collected, and the sample is stained using IHC to evaluate the expression of MMR proteins (MLH1, MSH2, MSH6, and PMS2).

  • Normal Expression: Intact MMR protein expression suggests proficient DNA repair.
  • Loss of Expression: Indicates MMR deficiency and possible microsatellite instability.

MMR testing helps guide treatment decisions, identify Lynch syndrome, and determine eligibility for immunotherapy.

Test code

9336

Specimen vol. and vacutainer information
SpecimenVacutainerVolume
Others (fx)Others
Paraffin BlockOthers2 NOS
TissueOthers2 NOS

Specimen stability information

Others (Fx)

Collection instructions

Site Of Biopsy Specimen + Clinical Details. Relevant Radiology Findings: X-Ray/Ct/Mri Report Images (Soft Copy). If tissue received, tissue processing will be charged.

Specimen rejection criteria

Test run frequency

'

Turn around time

6 Working Days

Performing locations

Department

  • Histopath

CPT and Loinc codes

Mismatch Repair Gene (MMR)

₹6700

Health Checkup Category

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