Alanine Aminotransferase (alt/sgpt)

The Alanine Aminotransferase (ALT) test, also known as the serum glutamate-pyruvate transaminase (SGPT) test, measures the level of the enzyme ALT in the blood. ALT is primarily found in the liver and plays a key role in amino acid metabolism by helping convert alanine and alpha-ketoglutarate into pyruvate and glutamate

The Alanine Aminotransferase (ALT) test is used for several important reasons related to liver health and function. Here’s a breakdown of why the ALT test is conducted:

1. Liver Health
2. Hepatitis
3. Fatty Liver Disease
4. Cirrhosis
5. Chronic Liver Conditions
6. Assess Baseline Liver Function

1. Individuals with Symptoms of Liver Disease
   • Jaundice: Yellowing of the skin and eyes.
   • Abdominal Pain: Discomfort or pain in the upper right abdomen.
   • Fatigue: Unexplained tiredness or weakness.
   • Dark Urine: Color changes in urine, such as darker than usual.
   • Itchy Skin: Persistent itching without a clear cause.
2. People with Risk Factors for Liver Disease
3. Individuals with a History of Hepatitis or Liver Disease
4. People on Medications with Potential Liver Effects
5. Individuals Undergoing Routine Health Screenings
6. Pre-Surgical or Pre-Medication Screening

Alanine Aminotransferase (ALT) is an enzyme primarily found in the liver, and to a lesser extent in other tissues such as the kidneys and heart. Here’s an in-depth look at ALT, including its function, clinical significance, and factors affecting its levels

Other Names: Serum Glutamate-Pyruvate Transaminase (SGPT), Alanine Transaminase