Double Stranded DNA (IFA)
Measures antibodies against double-stranded DNA (DsDNA), with titration, to assess the presence of lupus or other autoimmune conditions.
Overview of Double Stranded DNA (IFA) in Howrah
The Double Stranded DNA (dsDNA) (IFA) test detects antibodies against double-stranded DNA in the blood using the Indirect Immunofluorescence Assay (IFA) method. These antibodies are strongly associated with autoimmune diseases, particularly Systemic Lupus Erythematosus (SLE). The test plays an important role in supporting the diagnosis of lupus and helps doctors assess immune system activity when autoimmune disease is suspected. It is usually recommended along with other autoimmune tests to provide a more complete clinical picture.
Who Should Get This Test Done?
This test is recommended for individuals who:
● Are suspected of having Systemic Lupus Erythematosus (SLE).
● Have symptoms such as butterfly rash, joint pain, fatigue, pleuritis, or pericarditis.
● Have lupus nephritis or unexplained kidney inflammation.
● Are experiencing a suspected lupus flare.
● Have unexplained anemia, low white blood cell count, or low platelet count.
● Have low complement levels (C3/C4) along with autoimmune symptoms.
Why Consider This Test?
The dsDNA Antibody (IFA) test helps:
● Support the diagnosis of SLE, as anti-dsDNA antibodies are highly specific for lupus.
● Assess disease activity, especially during lupus flares.
● Monitor lupus nephritis, where rising antibody levels may indicate worsening kidney involvement.
● Guide treatment decisions by tracking changes in antibody titres over time.
● Predict disease progression, particularly when interpreted alongside complement levels and clinical findings.
More Information
Double-stranded DNA is the natural form of DNA found inside the body’s cells. In certain autoimmune conditions, the immune system mistakenly produces antibodies against this DNA, leading to inflammation and tissue damage. The IFA method is widely used for detecting these antibodies with high specificity. This test is typically interpreted together with clinical symptoms, medical history, and other laboratory investigations to support an accurate diagnosis.
Other Names of the Test
● Anti-dsDNA Antibody Test
● Anti-Double Stranded DNA Test
● dsDNA Antibody by Crithidia luciliae IFA
● Native DNA Antibody Test
● Lupus DNA Antibody Test
● Anti-dsDNA IFA Test
● Double Stranded DNA Antibody by Immunofluorescence
● SLE Antibody Test – dsDNA
● DNA Binding Antibody Test
Test included
- Dsdna
- Dilution
- Primary Intensity Of
- Endpoint Titre
Doctor information
Test code
1199
CPT and Loinc codes
Department
- Autoimmune-ifa
Turn around time
3 Working Days
Test run frequency
Tuesday,Thursday,Saturday TIME - 15:00
Performing locations
1 labs across India
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Serum | Yellow Vacutainer | 2 ML |
Specimen stability information
Serum
Package price
₹2700
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