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HBV Basal Core Promoter Mutation

Available viaHome Collection, Lab Visit
GenderMale & Female
Contains2 parameters
Earliest reports in6 Working Days
PreparationNo preparation needed

Overview of HBV Basal Core Promoter Mutation in Kharar

What is the HBV Basal Core Promoter Mutation test and why is it conducted?

 This test detects mutations in the basal core promoter (BCP) region of the Hepatitis B virus (HBV). These mutations are known to influence viral replication, progression of liver disease, and the risk of developing hepatocellular carcinoma (liver cancer). The test is crucial for identifying patients with a more aggressive form of HBV or those who might not respond well to standard antiviral treatments. It provides guidance on disease monitoring and therapeutic strategies.


How is the test performed?

A blood sample is collected and processed using molecular diagnostic techniques such as polymerase chain reaction (PCR) and DNA sequencing. These methods allow for the precise identification of mutations in the BCP region of the HBV genome. The most common mutations evaluated include the A1762T and G1764A variants, which are strongly associated with increased disease severity.


What do the results indicate?

Detection of BCP mutations suggests a higher risk of liver inflammation, fibrosis, or cancer, even if standard liver function tests appear normal. It may also correlate with lower levels of HBeAg (Hepatitis B e Antigen) in the blood despite active viral replication. This discordance can mislead clinicians unless molecular testing is done. As a result, patients with such mutations often require more rigorous follow-up and possibly more aggressive antiviral therapy.


Is this test used for everyone with Hepatitis B?

 While not routinely done in all HBV-positive patients, it is particularly useful in those with abnormal disease patterns, unclear HBeAg status, or rising liver enzymes. It is also recommended for patients with a family history of liver cancer or those being evaluated for liver transplant.


Do I need to prepare for this test?

There is no specific preparation required for this test. However, sharing your complete HBV treatment history and clinical background with your doctor ensures proper interpretation of the results in context.

Test included

HBV Basal Core Promoter Mutation includes 2 parameters

  • Hbv Basal Core Promoter Mutation
  • Hbv Viral Load

Test code

7475

CPT and Loinc codes

Department

  • Molecular Biology

Turn around time

6 Working Days

Test run frequency

Wednesday TIME - 10:00

Performing locations

1 labs across India

Specimen vol. and vacutainer information

SpecimenVacutainerVolume
Plasma EdtaLavender Vacutainer3 ml
SerumYellow Vacutainer3 ml

Specimen stability information

Plasma Edta, Serum

HBV Basal Core Promoter Mutation test price for other cities
City namePrice
HBV Basal Core Promoter Mutation test price in Chennai₹4600
HBV Basal Core Promoter Mutation test price in Gurugram₹4600
HBV Basal Core Promoter Mutation test price in Hyderabad₹4600
HBV Basal Core Promoter Mutation test price in Amritsar₹4600
HBV Basal Core Promoter Mutation test price in Kolkata₹4600
HBV Basal Core Promoter Mutation test price in Lucknow₹4600
HBV Basal Core Promoter Mutation test price in Mumbai₹4710
HBV Basal Core Promoter Mutation test price in Mysuru₹4600
HBV Basal Core Promoter Mutation test price in New delhi₹4600
HBV Basal Core Promoter Mutation test price in Bengaluru₹4600

HBV Basal Core Promoter Mutation

₹4600

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