Alanine Aminotransferase (ALT/SGPT)

The Alanine Aminotransferase (ALT) test, also known as the serum glutamate-pyruvate transaminase (SGPT) test, measures the level of the enzyme ALT in the blood. ALT is primarily found in the liver and plays a key role in amino acid metabolism by helping convert alanine and alpha-ketoglutarate into pyruvate and glutamate

Why consider this test?

The Alanine Aminotransferase (ALT) test is used for several important reasons related to liver health and function. Here’s a breakdown of why the ALT test is conducted:

1. Liver Health
2. Hepatitis
3. Fatty Liver Disease
4. Cirrhosis
5. Chronic Liver Conditions
6. Assess Baseline Liver Function

Who should get this test done?

1. Individuals with Symptoms of Liver Disease
   • Jaundice: Yellowing of the skin and eyes.
   • Abdominal Pain: Discomfort or pain in the upper right abdomen.
   • Fatigue: Unexplained tiredness or weakness.
   • Dark Urine: Color changes in urine, such as darker than usual.
   • Itchy Skin: Persistent itching without a clear cause.
2. People with Risk Factors for Liver Disease
3. Individuals with a History of Hepatitis or Liver Disease
4. People on Medications with Potential Liver Effects
5. Individuals Undergoing Routine Health Screenings
6. Pre-Surgical or Pre-Medication Screening

More information

Alanine Aminotransferase (ALT) is an enzyme primarily found in the liver, and to a lesser extent in other tissues such as the kidneys and heart. Here’s an in-depth look at ALT, including its function, clinical significance, and factors affecting its levels

Other Names: Serum Glutamate-Pyruvate Transaminase (SGPT), Alanine Transaminase