Ceruloplasmin, Serum

The Serum Ceruloplasmin test measures the level of ceruloplasmin, a copper-carrying protein, in the blood. Ceruloplasmin plays a key role in transporting copper and protecting cells from oxidative damage. This test is often used to help diagnose disorders related to abnormal copper metabolism, such as Wilson’s disease or Menkes disease. It can also provide insight into liver function and certain inflammatory conditions.

Why consider Serum Ceruloplasmin test?

This test is considered when there is a need to evaluate copper metabolism disorders, such as Wilson’s disease, where copper accumulates in the body. It is also useful in assessing liver function and detecting conditions that cause low ceruloplasmin levels, including certain genetic disorders or malnutrition. Additionally, the test may help investigate unexplained neurological or psychiatric symptoms linked to copper imbalance.

Who should get Serum Ceruloplasmin test done?

Individuals who:

• Show symptoms of Wilson’s disease, such as liver problems, neurological issues, or psychiatric symptoms
• Have a family history of copper metabolism disorders
• Experience unexplained liver dysfunction or cirrhosis
• Present with early-onset neurological symptoms like tremors or movement disorders
• Are being evaluated for conditions causing low ceruloplasmin, such as Menkes disease or malnutrition.

More Information about Serum Ceruloplasmin test

Ceruloplasmin is an enzyme that also functions as an antioxidant, helping to reduce oxidative stress in the body. Its levels can be influenced by factors such as inflammation, pregnancy, and hormonal changes, which may cause elevated ceruloplasmin without indicating disease. Low ceruloplasmin levels are not only linked to copper metabolism disorders but can also occur in conditions like nephrotic syndrome or malabsorption.

Other Names: Ceruloplasmin blood test, Copper transport protein test, Serum copper-binding protein test.