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Mismatch Repair Gene (MMR)

This panel tests for mutations in mismatch repair genes, which are critical in preventing DNA errors. It is particularly useful in the diagnosis of Lynch syndrome and related cancers.

Also known asmismatch repair gene ihcmmr protein testinglynch syndrome screeningdna repair ihc
Available viaHome Collection, Lab Visit
GenderMale & Female
Contains15 parameters
Earliest reports in6 Working Days
PreparationNo preparation needed

Overview of Mismatch Repair Gene (MMR) in Mumbai

What is the Mismatch Repair (MMR) Gene IHC Test?

This test analyzes tissue samples to detect the expression of mismatch repair (MMR) proteins using immunohistochemistry (IHC). MMR proteins repair DNA errors during cell division, and their loss indicates microsatellite instability (MSI), commonly associated with Lynch syndrome and colorectal cancer.


Who should get this test?

This test is recommended for:

Patients diagnosed with colorectal or endometrial cancer.
Individuals with a family history of Lynch syndrome.
Those with suspected hereditary cancer syndromes.



How is the test performed?

A tissue biopsy is collected, and the sample is stained using IHC to evaluate the expression of MMR proteins (MLH1, MSH2, MSH6, and PMS2).


What do the results indicate?


Normal Expression: Intact MMR protein expression suggests proficient DNA repair.
Loss of Expression: Indicates MMR deficiency and possible microsatellite instability.



Why is this test important?

MMR testing helps guide treatment decisions, identify Lynch syndrome, and determine eligibility for immunotherapy.

Test included

Mismatch Repair Gene (MMR) includes 15 parameters

  • Specimen
  • Request Letter
  • Additional Communication
  • Mlh1

  • Request Letter
  • Additional Communication
  • Msh2

  • Request Letter
  • Additional Communication
  • Msh6

  • Request Letter
  • Additional Communication
  • Pms2
  • Diagnosis
  • Comments

Test code

9336

CPT and Loinc codes

Department

  • Histopath

Turn around time

6 Working Days

Performing locations

1 labs across India

Specimen vol. and vacutainer information

SpecimenVacutainerVolume
Others (fx)Others
Paraffin BlockOthers2 NOS
TissueOthers2 NOS

Specimen stability information

Others (Fx)

Collection instructions

Site Of Biopsy Specimen + Clinical Details. Relevant Radiology Findings: X-Ray/Ct/Mri Report Images (Soft Copy). If tissue received, tissue processing will be charged.

Mismatch Repair Gene (MMR) test price for other cities
City namePrice
Mismatch Repair Gene (MMR) test price in Chennai₹6700
Mismatch Repair Gene (MMR) test price in Gurugram₹6700
Mismatch Repair Gene (MMR) test price in Hyderabad₹6700
Mismatch Repair Gene (MMR) test price in Amritsar₹6700
Mismatch Repair Gene (MMR) test price in Kolkata₹6700
Mismatch Repair Gene (MMR) test price in Lucknow₹6700
Mismatch Repair Gene (MMR) test price in Mysuru₹6700
Mismatch Repair Gene (MMR) test price in New delhi₹6700
Mismatch Repair Gene (MMR) test price in Bengaluru₹6700
Mismatch Repair Gene (MMR) test price in Chandigarh₹6700

Mismatch Repair Gene (MMR)

₹6955

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Mismatch Repair Gene (MMR) Test in Other Cities

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