Celiac Profile

The Celiac Profile is a comprehensive blood test that evaluates key antibodies associated with celiac disease, an autoimmune condition triggered by the consumption of gluten. The profile includes Tissue Transglutaminase (tTG) IgA, Deaminated Gliadin Peptide (DGP) IgA, and DGP IgG antibodies, providing a broad assessment of the body’s immune response to gluten. This combination of tests helps support the diagnosis of celiac disease and assists healthcare professionals in evaluating individuals with symptoms or risk factors suggestive of gluten-related autoimmune disorders.

Who should get this test done?

This test may be recommended for individuals who:

●     Have persistent digestive symptoms such as diarrhoea, bloating, abdominal pain, or unexplained weight loss.

●     Experience nutritional deficiencies or unexplained anaemia that may indicate poor nutrient absorption.

●     Have a family history of celiac disease or other autoimmune disorders.

●     Show symptoms such as chronic fatigue, delayed growth, or recurrent mouth ulcers that require evaluation for celiac disease.

●     Need further investigation for suspected gluten-related autoimmune disorders.

Why consider this test?

The Celiac Profile offers a comprehensive evaluation by measuring multiple antibodies associated with celiac disease in a single panel. Since immune responses to gluten can vary among individuals, assessing more than one antibody improves the overall evaluation and provides a broader understanding of the condition. The inclusion of both DGP antibodies and Tissue Transglutaminase IgA allows healthcare professionals to investigate suspected celiac disease more effectively and supports informed decisions regarding further diagnostic assessment and patient management.

More Information

This profile combines three important antibody markers that reflect different aspects of the immune response to gluten. Tissue Transglutaminase (tTG) IgA is one of the most widely used markers for celiac disease, while DGP IgA and DGP IgG antibodies provide additional information, particularly in individuals with varying immune responses. By evaluating these markers together, the profile offers a more complete assessment of gluten-related autoimmunity and serves as a valuable tool in the clinical evaluation of celiac disease.

Other Names

●     Celiac Disease Profile

●     Celiac Antibody Panel

●     Celiac Serology Panel

●     Gluten Sensitivity Antibody Profile

●     Celiac Screening Panel

●     Celiac Disease Antibody Profile