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BCR ABL 1 Kinase Domain Mutation Analysis

This test detects mutations in the kinase domain of the BCR-ABL gene, which may indicate resistance to certain leukemia treatments. It helps guide therapy choices in chronic myelogenous leukemia (CML).

Also known asbcr-abl kinase domain mutationbcr abl mutation analysisbcr abl 1 kinase domain mutation analysisleukemia gene mutation test (bcr-abl1)

Available via

Home Collection, Lab Visit

Contains

2 parameters

Earliest reports in

10 Working Days

Test details

BCR ABL 1 Kinase Domain Mutation Analysis Test in Mysuru Overview

Preparations

No special preparations needed

Test included
BCR ABL 1 Kinase Domain Mutation Analysis includes 2 parameters

  • Specimen
  • Bcr-abl 1 Kinase Domain Mutations
Frequently Asked Questions

This test detects mutations in the kinase domain of the BCR-ABL fusion gene, which can cause resistance to tyrosine kinase inhibitors (TKIs) used in treating chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL).

  • Patients with CML or Philadelphia chromosome-positive ALL who are not responding to TKIs.
  • Individuals experiencing disease relapse after TKI treatment.

  • Monitoring for drug resistance in long-term therapy.

A blood or bone marrow sample is analyzed using PCR and sequencing methods to identify mutations in the BCR-ABL gene.

  • Mutations detected: May suggest resistance to certain TKIs, requiring a change in treatment.

No mutations detected: The treatment may need to be adjusted due to other factors, not mutations.

Identifying mutations in BCR-ABL helps determine the most effective therapy and prevent disease progression.

Test code

5351

Specimen vol. and vacutainer information
SpecimenVacutainerVolume
Edta Whole BloodLavender Vacutainer3 ML

Specimen stability information

Edta Whole Blood

Specimen rejection criteria

Test run frequency

Every Day TIME - 10:00

Turn around time

10 Working Days

Performing locations

Department

  • Advanced Molecular Diagnostics R&d

CPT and Loinc codes

BCR ABL 1 Kinase Domain Mutation Analysis

₹11000

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