Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation
Tests for mutations in the DPD gene, which is responsible for metabolizing certain chemotherapy drugs. This test helps guide safe drug dosing.
Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Test in New Delhi Overview
No special preparations needed
- Preliminary Report
- Dihydropyrimidine Dehydrogenase Gene Mutation - Sequencing
This test identifies mutations in the DPD (dihydropyrimidine dehydrogenase) gene, which affect the body’s ability to metabolize fluoropyrimidine-based chemotherapy drugs.
This test is recommended for:
- Patients undergoing fluoropyrimidine (5-FU or capecitabine) chemotherapy.
- Individuals with severe reactions to fluoropyrimidine-based drugs.
A blood or buccal swab sample is analyzed using PCR or DNA sequencing.
- Positive Mutation: Increased risk of drug toxicity.
- No Mutation: Normal drug metabolism expected.
Identifying DPD mutations helps adjust chemotherapy dosage and prevent severe drug toxicity.
Test code
8384
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
Specimen stability information
Edta Whole Blood
Collection instructions
Clinical History
Specimen rejection criteria
Test run frequency
Every Day TIME - 09:30
Turn around time
7 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
CPT and Loinc codes
Package price
₹14500
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₹14500