Homocysteine, Serum/plasma

A homocysteine test measures the amount of homocysteine in a sample of your blood. Homocysteine is an amino acid. Amino acids are molecules that your body uses to make proteins.

Why consider this Test?

A homocysteine test measures the level of homocysteine, an amino acid in your blood. Elevated homocysteine levels can be a risk factor for heart disease, stroke, and other vascular problems, as it can damage the blood vessels and lead to clotting. This test is often used to assess cardiovascular health, particularly if you have a family history of heart disease or other risk factors.

Homocysteine levels can be influenced by several factors, including:

• Vitamin deficiencies: Lack of B vitamins like B6, B12, and folate can raise homocysteine levels.
• Genetic factors: Some people have genetic mutations that cause higher homocysteine levels.
• Kidney disease: Kidney problems can affect homocysteine processing.
• Lifestyle: Smoking, excessive alcohol use, and lack of physical activity may contribute to elevated level.

Who should get this Test Done?

A homocysteine test is typically recommended for individuals who are:

1. People with cardiovascular disease risk factors
2. Individuals with a history of blood clots
3. People with vitamin B12 or folate deficiencies
4. Individuals with a family history of high homocysteine levels
5. Older adults
6. Pregnant women (in certain cases)

More about test :

You may need this test if you have symptoms that suggest you lack vitamin B12 or folic acid. The symptoms may be very mild to severe and may include:

• Dizziness
• Fatigueand/or weakness
• Headache
• Heart palpitations (racing or pounding heart)
• Changes in the color of your skin or fingernails
• Sores on your tongue or in your mouth
• Tingling or numbness in your hands, feet, arms, and/or legs

Your provider may order this test if you have a high risk for low levels of vitamin B12 or folic acid because you:

• Have malnutrition
• Are an older adult. Older people often can't absorb enough vitamin B12 from food.
• Have alcohol use disorderor a drug addiction.

Your provider may recommend this test if you:

• Have had a heart attack or stroke
• Have one or more conditions that increase your risk for heart attack or stroke, such as high LDL "bad" cholesterolor high blood pressure