EGFR Mutation Detection, Tissue/Block
This test detects mutations in the EGFR gene, commonly associated with non-small cell lung cancer (NSCLC). Identifying EGFR mutations can help determine whether targeted therapies like tyrosine kinase inhibitors will be effective. It is crucial for personalized cancer treatment.
EGFR Mutation Detection, Tissue/Block Test in Rohtak Overview
What is EGFR mutation detection test?
EGFR mutation detection test analyzes a patient's tumor tissue to identify genetic mutations in the Epidermal Growth Factor Receptor (EGFR) gene, primarily for non-small cell lung cancer (NSCLC). EGFR mutation detection test helps determine if a patient's cancer is susceptible to certain tyrosine kinase inhibitor (TKI) drugs, enabling personalized treatment plans and improved patient outcomes.
Why consider EGFR mutation detection test?
EGFR mutation detection test helps oncologists choose the most effective treatment, guiding whether a patient may benefit from a TKI such as gefitinib or erlotinib, and can also detect resistance mutations.
- Guides Targeted Therapy
- Personalized Treatment
- Detects Resistance Mutations
Who should get this EGFR mutation detection test?
EGFR mutation detection test is recommended by clinicians for
- Patients primarily those with newly diagnosed non-small cell lung cancer (NSCLC), especially adenocarcinoma, to determine if their tumor has an EGFR gene mutation
- Patients with advanced NSCLC, especially adenocarcinoma or NSCLC‑NOS with adenocarcinoma features, as part of standard biomarker workup regardless of age, sex, or smoking history.
- Cases with sufficient tumor in FFPE blocks or slides; cytology cell blocks can also be suitable when tissue is limited, per lab validation.
More Information about EGFR mutation detection test
EGFR mutation refers to a change in the epidermal growth factor receptor gene that causes continuous activation of its tyrosine kinase signaling, driving tumor growth, most commonly in non‑small cell lung cancer (NSCLC). The two most common mutations are exon 19 deletions and the exon 21 L858R point mutation, together accounting for about 85–90% of EGFR mutations in NSCLC.
Other Names: EGFR Mutation Analysis, EGFR Mutation detection, EGFR gene test, EGFR Exon 18–21 Analysis; EGFR Molecular Testing on FFPE Block.
No special preparations needed
- Exon 18g719x Mutation
- Exon 19 Deletions
- Exon 20 S768i Mutation
- Exon 20 T790m Mutation
- Exon 20 Insertions
- Exon 21 L858r Mutation
- Exon 21 L861q Mutation
- Block Identification Number
- Clinical Details
Test code
RD1405
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Paraffin Block | Others | 1 NOS |
Specimen stability information
Paraffin Block
Collection instructions
If Tissue Received; Tissue Processing Will Be Charged Seperately. Site Of Biopsy & Clinical Details Mandatory If Tissue Recd.
Specimen rejection criteria
Test run frequency
Every Day TIME - 09:30
Turn around time
5 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
CPT and Loinc codes
Package price
₹8500
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₹8500