17-A-Hydroxyprogesterone

What is the 17-α-Hydroxyprogesterone Test?

This test measures 17-α-hydroxyprogesterone (17-OHP), a precursor steroid involved in cortisol synthesis.


Who should get this test?

This test is recommended for:

Newborns suspected of congenital adrenal hyperplasia (CAH).
Women with irregular menstrual cycles or hirsutism.
Patients with adrenal gland disorders.



How is the test performed?

A blood sample is taken and analyzed using immunoassays or mass spectrometry.


What do the results indicate?


High 17-OHP Levels: Suggests CAH, adrenal tumors, or enzyme deficiencies.
Normal Levels: Rules out adrenal hyperplasia.



Why is this test important?

Early detection of CAH helps in prompt management and prevents life-threatening complications.