AFB Susc. Ofloxacin

What is the AFB Susceptibility to Ofloxacin test?

This test determines the sensitivity of Mycobacterium tuberculosis (MTB) to ofloxacin, a fluoroquinolone antibiotic used in multidrug-resistant TB (MDR-TB) treatment.


When is this test recommended?

It is performed for TB patients who:

Show resistance to first-line drugs
Experience treatment failure or relapse
Require tailored MDR-TB therapy



How is the test performed?

A sputum or tissue sample is cultured, and drug susceptibility is evaluated using automated systems such as MGIT or phenotypic assays.


What do the results indicate?


Susceptible: Ofloxacin is effective in treating the infection.
Resistant: Indicates the need for alternative antibiotics.



Can resistance develop during treatment?

Yes, improper use or incomplete treatment can lead to the emergence of drug-resistant strains.