DOG 1
DOG-1 is a marker highly expressed in gastrointestinal stromal tumors (GISTs). This test is essential for diagnosing GISTs and distinguishing them from other soft tissue sarcomas. DOG-1 positivity is key in identifying these tumors when KIT (CD117) is negative.
DOG 1 Test in Varanasi Overview
No special preparations needed
- Request Letter
- Additional Communication
- Dog 1
A positive DOG1 result strongly supports the diagnosis of GIST. Negative results may require additional testing using other tumor markers to confirm the diagnosis.
This test is important in differentiating GISTs from other soft tissue tumors, particularly when diagnosing gastrointestinal tract tumors. It supports histopathological confirmation and helps guide treatment.
A tissue sample from a suspected tumor is processed and stained with antibodies against DOG1 protein. The stained tissue is examined under a microscope to assess the presence of DOG1 expression.
DOG1 (Discovered On GIST-1) is an immunohistochemical test used to identify gastrointestinal stromal tumors (GISTs). It is highly sensitive and specific for diagnosing GISTs even in cases where other markers are negative.
No specific preparations are needed. The accuracy of the result depends on the quality of the biopsy and laboratory processing.
Test code
Z272K
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Paraffin Block | Others | 2 NOS |
| Tissue | Others | 2 NOS |
Specimen stability information
Paraffin Block, Tissue
Collection instructions
Site Of Biopsy Specimen + Clinical Details. Relevant Radiology Findings: X-Ray/Ct/Mri Report Images (Soft Copy). If tissue received, tissue processing will be charged.
Specimen rejection criteria
Test run frequency
Every Day TIME - 08:00
Turn around time
3 Working Days
Performing locations
Department
- Histopath
CPT and Loinc codes
Package price
₹2700
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₹2700