Endomysial IgA Antibody with Titre

What is the Endomysial IgA Antibodies test?

This test detects the presence of IgA antibodies against endomysium, a component of connective tissue in muscles. These antibodies are highly specific for celiac disease.


Why is this test done?

It is used to help diagnose celiac disease and to monitor dietary compliance in patients who are already diagnosed. It is often performed alongside other tests such as tissue transglutaminase antibodies.


How is the test performed?

A blood sample is collected, and the serum is tested using indirect immunofluorescence to identify IgA antibodies targeting endomysial tissue.


What do the results mean?

A positive result indicates a high likelihood of celiac disease, especially when correlated with symptoms and other laboratory tests. A negative result usually rules out the disease.


Are there any precautions or preparations required?

No fasting is needed. However, the patient should be on a gluten-containing diet before testing to avoid false negatives.