MPN Reflex Panel
The MPN Reflex Panel is performed when initial myeloproliferative neoplasm tests return inconclusive results. It further analyzes genetic markers for a more comprehensive diagnosis.
MPN Reflex Panel Package Overview
What is MPN Reflex Panel Test?
The MPN Reflex Panel is a genetic blood test that diagnoses and classifies myeloproliferative neoplasms (MPNs), a type of blood cancer where the bone marrow produces too many blood cells. The test analyses key genes BCR ABL QUALITATIVE, JAK2 V617F MUTATION DETECTION, CALR GENE MUTATION DETECTION, JAK2 EXON 12 MUTATION DETECTION, MPL MUTATION DETECTION
Why consider MPN REFLEX PANEL Test?
- Diagnostic clarity: Identifies canonical driver mutations present in the vast majority of non‑CML MPNs (JAK2 in most PV and ~50–60% ET/PMF; CALR in many JAK2‑negative ET/PMF; MPL in a smaller subset), distinguishing clonal disease from reactive cytoses.
- Prognosis and management: Mutation class and burden support risk stratification (e.g., thrombotic risk in PV/ET), influence cytoreductive therapy decisions, and inform transplant considerations in MF.
- Efficiency: Reflexing automatically when the preceding test is negative minimizes repeat phlebotomy, shortens time to result, and ensures adherence to evidence‑based testing order.
Who should get this MPN REFLEX PANEL Test?
- Individuals with persistent erythrocytosis, thrombocytosis, or leukocytosis where clinical evaluation suggests a clonal MPN rather than reactive causes.
- Patients with suspected PV (JAK2 V617F/exon 12), ET, or PMF after initial clinical, CBC, and marrow findings; also considered in MDS/MPN overlap with thrombocytosis to clarify driver status
More Information about MPN REFLEX PANEL Test
The panel's comprehensive genetic analysis helps to accurately diagnose and classify various myeloproliferative neoplasms.
By identifying specific genetic mutations, the test provides valuable information for physicians to make appropriate treatment plans and manage the condition effectively.
OTHER NAMES: Myeloproliferative Neoplasm Reflex Panel BCR ABL QUALITATIVE, JAK2 V617F MUTATION DETECTION, CALR GENE MUTATION DETECTION, JAK2 EXON 12 MUTATION DETECTION, MPL MUTATION DETECTION Non‑CML MPN Molecular Panel, MPN Core Diagnostic Panel
No special preparations needed
- Specimen Source
- Jak2 V617f Mutation Detection
- Jak2 Exon 12 Mutation
- Specimen Source
- Bcr/abl Gene
- Preliminary Report
- Mpl Mutation
- Calreticulin Gene Mutation Detection
Test code
RD1322RFX
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Bone Marrow | Others | 15 NOS |
| Edta Whole Blood | Lavender Vacutainer | 18 ML |
Specimen stability information
Bone Marrow, Edta Whole Blood
Collection instructions
Clinical History
Specimen rejection criteria
Test run frequency
'
Turn around time
10 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
CPT and Loinc codes
Package price
₹16500
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₹16500