COMPREHENSIVE NSCLC PANEL 2

Similar to the DAKO 22C3 test, this NSCLC panel analyzes genetic mutations and PD-L1 expression, but using the SP263 antibody. PD-L1 expression is a key factor in deciding whether immunotherapy is appropriate for lung cancer patients. The test offers a more tailored treatment approach.

Available via

Home Collection, Lab Visit

Contains

18 parameters

Earliest reports in

Same Day

Test details

COMPREHENSIVE NSCLC PANEL 2 Package Overview

What is Comprehensive NSCLC Panel test?

Comprehensive NSCLC Panel is a combination of 13 key mutations in lung cancer along with PDL1 (SP 263) Ventana testing. NSCLC stands for Non-Small Cell Lung Cancer, which is the most prevalent type of lung cancer in India. NSCLC panel is an NGS based test which offers complete genotyping solutions by amazing 13 genes relevant to lung cancer. It typically covers EGFR, ALK, ROS1, BRAF, MET, RET, ERBB2/HER2, KRAS and NTRK1/2/3, alongside other actionable or resistance‑associated genes.

PDL1 (SP 263) Ventana test detects PD-L1 protein in people diagnosed with non-small cell lung cancer. If the PD-L1 protein is present, it indicates that the patient may benefit from immunotherapy drugs.

What is Comprehensive NSCLC Panel test?

Clinicians should consider & recommend NSCLC Panel for-

  • Comprehensive therapy guidance as it assesses relevant 13 genes & PDL1 SP263 Ventana (for immunotherapy) related to NSCLC to match patients to approved targeted therapies and trials.
  • Consolidates multiple single‑gene tests into one assay, conserving limited tissue and shortening time to a clinically actionable, tumor‑board‑ready report.
  • Detects resistance mutations at progression and samples tumor heterogeneity more effectively than sequential testing, supporting dynamic treatment adaptation.

Why consider Comprehensive NSCLC Panel test?

Comprehensive NSCLC Panel tests identify specific genetic mutations and PD-L1 expression in Non-Small Cell Lung Cancer (NSCLC) patients to guide targeted therapy selection, which can lead to more effective treatment and better patient outcomes.

Who should get this Comprehensive NSCLC Panel test?

Clinicians should consider & recommend NSCLC Panel for-

  • Newly diagnosed stage III/IV non‑squamous NSCLC (and squamous with clinical features suggesting a driver, such as younger age or minimal smoking) where broad, upfront testing can match to targeted therapies or trials.
  • Cases with limited tissue or when rapid results are crucial, where a single panel conserves sample and shortens time to an actionable, tumor‑board‑ready report.
  • Patients progressing on targeted therapy who need resistance profiling (e.g., EGFR, ALK, ROS1, MET mechanisms) to guide the next line of treatment.
  • Individuals considered for immunotherapy or combination strategies, where panel results help contextualize choices alongside PD‑L1 and clinical factors.

More Information about Comprehensive NSCLC Panel test

NSCLC stands for non-small cell lung cancer, the most common category of lung cancer that includes adenocarcinoma, squamous cell carcinoma, and large cell carcinoma, and is managed with combinations of surgery, radiation, chemotherapy, targeted therapy, and immunotherapy based on stage and biomarkers. NSCLC (non-small cell lung cancer) is the most common type of lung cancer, making up about 80% of all lung cancer cases. It is a broad term for several types of epithelial lung cancers, with the main subtypes being adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. 

Other names: NSCLC panel; NSCLC test, Lung cancer targeted panel; NSCLC comprehensive genomic profiling (CGP) panel; Lung cancer panel, Lung cancer profiler next, Lung cancer NGS panel, Lung cancer 13 gene panel, NSCLC panel with PDL1, Lung cancer panel with PDL1 SP263, Lung cancer panel with PDL1 Ventana, NSCLC panel with PDL1 sp263.

Preparations

No special preparations needed

Test included
COMPREHENSIVE NSCLC PANEL 2 includes 18 parameters

  • Request Letter
  • Clinical Data
  • Specimen Type
  • Gross Appearance
  • Impression
  • Microscopy
  • Comment
  • Addendum
  • Reference
  • Note

  • Egfr Exon 18
  • Egfr Exon 19
  • Egfr Exon 20
  • Egfr Exon 21
  • Block Identification Number

  • Somatic Dna Mutation Status
  • Somatic Rna Fusion Status
  • Block Id

Test code

10169A

Specimen vol. and vacutainer information
SpecimenVacutainerVolume
BlocksOthers
Paraffin BlockOthers3 NOS
SlidesSlider Mail Box2 NOS
TissueOthers

Specimen stability information

Blocks, Tissue

Collection instructions

Age,Gender,Clinical history required

Specimen rejection criteria

Test run frequency

'

Turn around time

Same Day

Performing locations

Department

  • Coe Cytology
  • Marketing

CPT and Loinc codes

COMPREHENSIVE NSCLC PANEL 2

24500

Health Checkup Category

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Complete Care Packages

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COMPREHENSIVE NSCLC PANEL 2 Package in Other Cities

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