MLH1 PROMOTER HYPERMETHYLATION
MLH1 hypermethylation testing evaluates the methylation status of the MLH1 gene, a key component of DNA mismatch repair. Its detection is important for diagnosing Lynch syndrome and other cancers.
MLH1 PROMOTER HYPERMETHYLATION Test in Bengaluru Overview
No special preparations needed
- Mlh1 Promoter Hypermethylation
- Block Identification Number
- Clinical Details
This test detects methylation of the MLH1 gene promoter, which can silence the gene and contribute to cancer development.
It is used in the evaluation of Lynch syndrome and in determining whether mismatch repair deficiency in colorectal cancer is due to sporadic causes.
Tumor tissue obtained through biopsy or surgery is analyzed for MLH1 methylation status.
Hypermethylation indicates likely sporadic tumorigenesis, while absence may suggest inherited cancer syndromes.
No preparation is needed by the patient, though a formal pathology report is required.
Test code
RD1447
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Tissue | Others | 1 NOS |
Specimen stability information
Tissue
Collection instructions
Site Of Biopsy & Clinical Details Mandatory If Tissue Recd.
Specimen rejection criteria
Test run frequency
Every Day TIME - 10:30
Turn around time
8 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
CPT and Loinc codes
Package price
₹7100
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₹7100