SICKLING TEST, EDTA WHOLE BLOOD

The sickling test screens for sickle cell disease or trait by detecting abnormal hemoglobin S in red blood cells.

People with a family history of sickle cell disease, unexplained anemia, or symptoms like pain crises and fatigue should take this test.

A blood sample is mixed with a chemical that induces sickling of red blood cells, which is then examined under a microscope.

A positive result suggests sickle cell disease or trait, while a negative result indicates normal hemoglobin.

Confirmatory tests like hemoglobin electrophoresis or genetic testing may be required for a definitive diagnosis.