Chimerism (Pre-Transplantation)
A small tissue biopsy is processed and examined to detect cellular abnormalities, cancer, or infections. The sample is analyzed under a microscope using various stains and techniques. It is commonly used to diagnose conditions like skin cancers, liver disease, and gastrointestinal disorders.
Chimerism (Pre-Transplantation) Test in Mangaluru Overview
No special preparations needed
- Name Of The Donor
- Chimerism Pre-transplantation
- Red Chilli
- Remarks / Recommendations
This is a preparatory test and does not yield diagnostic outcomes. The STR profiles generated are stored for comparison with post-transplant chimerism assays.
Post-transplant, repeat chimerism tests are performed to determine the proportion of donor vs. recipient cells, guiding the success of engraftment and need for therapeutic intervention.
Pre-transplant chimerism testing is used to establish baseline DNA profiles of the recipient and donor prior to hematopoietic stem cell transplantation (HSCT). It allows for accurate post-transplant monitoring of donor cell engraftment.
It is performed prior to allogeneic HSCT to record genetic differences between donor and recipient, which are crucial for post-transplant follow-up.
DNA is extracted from blood or buccal swabs of the donor and recipient, and STR (short tandem repeat) markers are analyzed using PCR-based methods.
Test code
RD1452
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
Specimen stability information
Edta Whole Blood, Edta Whole Blood
Specimen rejection criteria
Test run frequency
'
Turn around time
7 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
- Eia - Infectious Section
- Corporate
- Local Send Out
CPT and Loinc codes
Package price
₹12400
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₹12400