O6-Methylguanine Methyltransferase (MGMT) Promoter
This test assesses the methylation status of the MGMT promoter gene in tumors. It helps predict the response to chemotherapy, especially in glioblastoma and other cancers.
O6-Methylguanine Methyltransferase (MGMT) Promoter Test in Mangaluru Overview
No special preparations needed
- Mgmt Promoter Methylation
The MGMT test evaluates the methylation status of the MGMT gene, which affects the tumor’s response to alkylating agents in glioblastoma treatment.
Patients with newly diagnosed glioblastoma or other high-grade brain tumors should undergo this test to guide treatment decisions.
A tissue sample from the tumor is analyzed using methylation-specific PCR (MS-PCR) to assess MGMT gene methylation.
Positive results indicate MGMT promoter methylation, suggesting a better response to alkylating chemotherapy agents like temozolomide.
Treatment plans may include alkylating agents to enhance therapeutic outcomes.
Test code
RD1469
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 2 ML |
| Paraffin Block | Others | 1 ML |
| Plasma Cit.frozen | Blue Vacutainer | 1 ML |
Specimen stability information
Paraffin Block
Collection instructions
Site Of Biopsy & Clinical Details Mandatory If Tissue Recd
Specimen rejection criteria
Test run frequency
Every Day TIME - 10:00
Turn around time
8 Working Days
Performing locations
Department
- Advanced Molecular Diagnostics R&d
CPT and Loinc codes
Package price
₹7500
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₹7500