C-MYC (8Q24) GENE REARRANGEMENT BY FISH, TISSUE
This test detects rearrangements in the C-MYC gene located on chromosome 8q24, which are commonly associated with certain cancers, including Burkitt lymphoma. It helps in the diagnosis, prognosis, and treatment planning for related malignancies.
C-MYC (8Q24) GENE REARRANGEMENT BY FISH, TISSUE Test in Mangaluru Overview
No special preparations needed
- Specimen
- Block Identification Number
- Number Of Observers
- Total Number Of Cells Analysed
- Interpretation
The C-MYC 8q24 Gene Arrangement test detects rearrangements involving the C-MYC gene on chromosome 8, which are often seen in Burkitt lymphoma and other aggressive B-cell lymphomas.
Patients with suspected or confirmed lymphoma, particularly Burkitt lymphoma or diffuse large B-cell lymphoma, should undergo this test.
A tissue or bone marrow sample is analyzed using fluorescence in situ hybridization (FISH) or PCR to detect C-MYC gene rearrangements.
Positive results indicate the presence of a C-MYC gene rearrangement, which is associated with aggressive lymphomas and poor prognosis.
A positive result may necessitate intensive chemotherapy, targeted therapies, or bone marrow transplantation.
Test code
8755
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Others (fx) | Others | 1 |
Specimen stability information
Others (Fx)
Collection instructions
Formalin-Fixed (10% Buffered Formalin For 24-48 Hrs), Paraffin-Embedded (Ffpe) Tissue Specimens. Transport Tissue Block Or 3 Unstained Slides/ Sample (4-Micron Thick Sections) Containing Malignant Tissue On Positively Charged Slides. * Time And Duration Of Fixation Should Be Mentioned On The Trf.* Required Clinical Details, Include Surgical Pathology Report.
Specimen rejection criteria
Test run frequency
Every Day TIME - 07:00
Turn around time
10 Working Days
Performing locations
Department
- Cytogenetics
CPT and Loinc codes
Package price
₹6000
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₹6000