OSMOTIC FRAGILITY TEST, BLOOD
This test assesses the ability of red blood cells to resist hemolysis when exposed to changes in osmotic pressure. It is used to diagnose conditions like hereditary spherocytosis and other blood disorders.
Also known asOsmotic Fragility TestBlood Osmotic Fragility TestBlood
Test details
OSMOTIC FRAGILITY TEST, BLOOD Test in Mumbai Overview
About the test :
The Osmotic Fragility Test (OFT) measures how easily red blood cells (RBCs) burst (hemolyze) when exposed to varying concentrations of salt (hypotonic) solutions.
- It evaluates the stability and integrity of red blood cell membranes.
- Helps detect abnormal red blood cell shapes or fragility that can lead to hemolytic anemia.
Why the Test Is Ordered
1. Suspected hereditary red blood cell disorders
- Spherocytosis (RBCs are sphere-shaped and fragile)
- Elliptocytosis (RBCs are elliptical)
2. Unexplained anemia
- Hemolytic anemia (RBCs destroyed faster than they are made)
- Unexplained jaundice
3. Pre- or post-splenectomy evaluation
- To confirm diagnosis of hereditary spherocytosis before surgery
4. Investigate hemolysis from other causes
- Autoimmune hemolytic anemia
- Certain infections or medications
Clinical Significance
- Helps diagnose specific red blood cell membrane disorders
- Guides treatment decisions for hemolytic anemia
- Can indicate need for further genetic or hematology testing
Preparations
No special preparations needed
Test included
OSMOTIC FRAGILITY TEST, BLOOD includes 3 parameters
- Red Cell Lysis Begins At
- Red Cell Lysis Ends At
- 50% Lysis At
Test code
5113
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Edta Whole Blood | Lavender Vacutainer | 3 ML |
| Heparin Whole Blood | Green Vacutainer | 3 ML |
Specimen stability information
Edta Whole Blood, Heparin Whole Blood
Specimen rejection criteria
Test run frequency
Every Day TIME - 10:00 , 14:30
Turn around time
Next Day
Performing locations
Department
- Haemotology
CPT and Loinc codes
OSMOTIC FRAGILITY TEST, BLOOD
Package price
₹1070
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