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Osmotic Fragility Test

Available viaHome Collection, Lab Visit
GenderMale & Female
Contains3 parameters
Earliest reports inNext Day
PreparationNo preparation needed

Overview of Osmotic Fragility Test in Mangaluru

About the test :

The Osmotic Fragility Test (OFT) measures how easily red blood cells (RBCs) burst (hemolyze) when exposed to varying concentrations of salt (hypotonic) solutions.

  • It evaluates the stability and integrity of red blood cell membranes.
  • Helps detect abnormal red blood cell shapes or fragility that can lead to hemolytic anemia.

Why the Test Is Ordered

1. Suspected hereditary red blood cell disorders

  • Spherocytosis (RBCs are sphere-shaped and fragile)
  • Elliptocytosis (RBCs are elliptical)

2. Unexplained anemia

  • Hemolytic anemia (RBCs destroyed faster than they are made)
  • Unexplained jaundice

3. Pre- or post-splenectomy evaluation

  • To confirm diagnosis of hereditary spherocytosis before surgery

4. Investigate hemolysis from other causes

  • Autoimmune hemolytic anemia
  • Certain infections or medications

Clinical Significance

  • Helps diagnose specific red blood cell membrane disorders
  • Guides treatment decisions for hemolytic anemia
  • Can indicate need for further genetic or hematology testing

Test included

Osmotic Fragility Test includes 3 parameters

  • Red Cell Lysis Begins At
  • Red Cell Lysis Ends At
  • 50% Lysis At

Test code

5113

CPT and Loinc codes

Department

  • Haemotology

Turn around time

Next Day

Test run frequency

Every Day TIME - 10:00 , 14:30

Performing locations

55 labs across India

Specimen vol. and vacutainer information

SpecimenVacutainerVolume
Edta Whole BloodLavender Vacutainer3 ML
Heparin Whole BloodGreen Vacutainer3 ML

Specimen stability information

Edta Whole Blood, Heparin Whole Blood

Osmotic Fragility Test test price for other cities
City namePrice
Osmotic Fragility Test test price in Hyderabad₹495
Osmotic Fragility Test test price in Kolkata₹725
Osmotic Fragility Test test price in Lucknow₹600
Osmotic Fragility Test test price in Mumbai₹1070
Osmotic Fragility Test test price in Mysuru₹800
Osmotic Fragility Test test price in Bengaluru₹385

Osmotic Fragility Test

₹1100

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