Cyclin D1, Tissue/Paraffin Block

The Cyclin D1, Tissue Paraffin Block test is an immunohistochemistry (IHC) assay performed on a paraffin-embedded tissue sample to detect the presence of the Cyclin D1 protein. Cyclin D1 plays an important role in regulating cell growth and division, and abnormal expression may be seen in certain types of cancers. This test helps pathologists evaluate tissue samples more accurately and supports the diagnosis, classification, and characterization of specific tumors, particularly when used alongside other clinical and laboratory findings.

Who Should Get This Test Done?

This test may be recommended for individuals who:

●     Have a tissue biopsy that requires further evaluation for suspected cancer.

●     Need additional testing to help classify or confirm certain lymphoma subtypes.

●     Have tumors that require immunohistochemical marker analysis for accurate diagnosis.

●     Require detailed pathological assessment to guide treatment planning.

●     Need supplementary testing when routine histopathology findings are inconclusive.

Why Consider This Test?

Some tumors may appear similar under a microscope, making it challenging to reach a definitive diagnosis based on routine examination alone. The Cyclin D1, Tissue Paraffin Block test provides additional information by identifying the expression of the Cyclin D1 protein within tumor cells. This helps distinguish between different types of cancers, improves diagnostic accuracy, and provides valuable insights that assist healthcare providers in making informed decisions about further evaluation and management.

More Information

This test is performed on a formalin-fixed, paraffin-embedded tissue specimen using immunohistochemistry. Cyclin D1 is a cell cycle regulatory protein involved in controlling the transition of cells through different phases of growth. Assessing its expression is an important part of pathological evaluation in selected cancers and is often combined with other immunohistochemical markers to provide a comprehensive understanding of the tissue sample.

Other Names

●     Cyclin D1 Immunohistochemistry (IHC)

●     Cyclin D1 IHC, Tissue

●     Cyclin D1 Marker, Paraffin Block

●     Cyclin D1 Immunostaining

●     BCL-1 (Cyclin D1) Immunohistochemistry Test