ABPA Screen (Total IgE, Specific IgE Aspergillus fumigatus)

What is ABPA SCREEN (TOTAL IGE, SPECIFIC IGE AF) test?

The ABPA Screen is a blood test used to evaluate allergic bronchopulmonary aspergillosis (ABPA), a hypersensitivity reaction to the fungus Aspergillus fumigatus.

• The ABPA SCREEN test measures:
1. Total IgE: Overall level of immunoglobulin E in the blood, which rises in allergic and hypersensitivity reactions.
2. Specific IgE for Aspergillus fumigatus (AF): Detects IgE antibodies specifically directed against Aspergillus fumigatus.
• Elevated levels indicate allergic sensitization to Aspergillus and help in diagnosing ABPA, which commonly affects patients with asthma or cystic fibrosis.

Why consider ABPA SCREEN (TOTAL IGE, SPECIFIC IGE AF) test?

This ABPA SCREEN test is important to:

• Detect allergic bronchopulmonary aspergillosis (ABPA) in patients with asthma or cystic fibrosis.
• Evaluate severity of allergic response and monitor disease progression.
• Assist in treatment planning, including corticosteroids or antifungal therapy.
• Monitor response to therapy and detect relapses in ABPA.

Who should get this ABPA SCREEN (TOTAL IGE, SPECIFIC IGE AF) test?

This ABPA SCREEN test is recommended for:

• Patients with asthma or cystic fibrosis showing worsening respiratory symptoms (wheeze, cough, mucus plugging).
• Individuals with recurrent pulmonary infiltrates or unexplained lung function decline.
• Patients suspected of ABPA based on clinical signs or imaging.
• Clinicians monitoring treatment response in known ABPA patients.

More Information

OTHER NAMES: Allergic Bronchopulmonary Aspergillosis Screening Test, Total and Specific IgE Aspergillus Test, ABPA IgE Panel

ABPA (Allergic Bronchopulmonary Aspergillosis) is an allergic reaction in the lungs caused by hypersensitivity to the fungus Aspergillus fumigatus. It primarily affects individuals with asthma or cystic fibrosis, leading to lung inflammation, airway damage, and mucus buildup if left untreated.

Symptoms of ABPA:

• Wheezing, cough, and shortness of breath
• Production of thick or brownish mucus
• Recurrent lung infections or pulmonary infiltrates
• Fever or malaise during exacerbations