Bk Virus Dna Quantitative

What is BK Virus DNA Quantitative test?

The BK Virus DNA Quantitative test is a real-time PCR assay used to measure the amount of BK polyomavirus DNA (viral load) in plasma samples. It aids in detecting active infection and monitoring disease progression, particularly in transplant recipients. By providing a numerical viral load that can be tracked over time, the test helps assess the risk of BK virus–associated nephropathy and hemorrhagic cystitis. BK virus is a common latent virus that can reactivate in individuals with weakened immune systems, and this test plays a crucial role in identifying and managing such reactivations.

Why consider BK Virus DNA Quantitative test?

• To detect active BK virus infection, especially in immunocompromised patients.
• To monitor BK virus levels in kidney or bone marrow transplant recipients to prevent or manage complications such as BK virus nephropathy.
• To guide treatment decisions and assess the effectiveness of antiviral therapy.
• To prevent damage to transplanted organs caused by BK virus reactivation.

Who should get tested for BK Virus DNA Quantitative test?

• Kidney or bone marrow transplant patients at risk of BK virus reactivation.

• Patients with weakened immune systems due to immunosuppressive therapy or diseases.
• Healthcare providers may order this test to monitor viral activity and prevent organ damage.

More Information

OTHER NAMES: BK virus viral load test, BK virus quantitative PCR, BK virus DNA test, BK viral load; BKV DNA quantitative PCR; BKV PCR, quantitative; Polyomavirus BK, quantitative.

BK virus (Human polyomavirus 1) is a small, non-enveloped, double-stranded DNA virus of the Polyomaviridae family with lifelong latency in renal tubular and urothelial cells after primary infection in childhood. In kidney transplant recipients, reactivation can cause BK virus–associated nephropathy, often presenting as rising serum creatinine and may mimic rejection, making biopsy important for diagnosis.