Protein Electrophoresis
A test that separates serum proteins into different fractions based on their electrical charge, helping diagnose conditions like multiple myeloma, liver disease, and chronic inflammation. It is important for detecting monoclonal gammopathies or protein imbalances. Useful for assessing protein distribution in systemic diseases.
Protein Electrophoresis Test in New Delhi Overview
What is Serum protein electrophoresis Test?
A serum protein electrophoresis (SPEP) test analyzes the different proteins in your blood serum to diagnose and monitor health conditions like multiple myeloma, liver disease, kidney disease, and chronic infections.
The serum protein electrophoresis (SPEP) test separates blood proteins into fractions (albumin, alpha-1, alpha-2, beta, gamma) to detect abnormal patterns such as a monoclonal “M‑protein” seen in plasma cell disorders.
Why consider Serum protein electrophoresis Test?
- Detect and monitor monoclonal gammopathies such as multiple myeloma, MGUS, Waldenström macroglobulinemia, and AL amyloidosis.
- Investigate abnormal total protein/albumin results, hypercalcemia, anemia, renal impairment, bone pain, recurrent infections, or unexplained elevated ESR.
- It helps evaluate unexplained high total protein, low albumin with high total protein, and symptoms suggestive of monoclonal gammopathies
Who should get this Serum protein electrophoresis Test?
- Individuals with clinical or laboratory features suggestive of plasma cell disorders (anemia, bone pain/lesions, hypercalcemia, renal dysfunction, proteinuria) or an unexplained high globulin gap.
- Patients needing evaluation of chronic inflammation, liver disease patterns, nephrotic syndrome, or immunodeficiencies where characteristic electrophoretic patterns aid assessment.
More Information about Serum protein electrophoresis Test
Blood protein (serum proteins) refers mainly to albumin and globulins that circulate in blood and perform transport, immune, and regulatory functions; abnormal levels or patterns can signal liver, kidney, inflammatory, or plasma cell disorders. The common clinical assessment is serum protein electrophoresis, which separates proteins into albumin, alpha-1, alpha-2, beta, and gamma regions to look for monoclonal spikes and other diagnostic patterns.
OTHER NAMES: Serum Protein Electrophoresis, SPE test, SPEP test, Protein Electrophoresis, Blood Serum Protein Electrophoresis
No special preparations needed
- Total Protein
- Albumin
- Alpha 1 Globulin
- Alpha 2 Globulin
- Beta 1 Globulin
- Beta 2 Globulin
- Gamma Globulin
- Myeloma Band
- M-spike
- Final Impression
- Comments
Test code
1580M
Specimen vol. and vacutainer information
| Specimen | Vacutainer | Volume |
|---|---|---|
| Serum | Yellow Vacutainer | .2 ML |
Specimen stability information
Serum
Collection instructions
10-12 hours fasting ( Over night Fasting) is recommended. Patient can drink water during fasting period. Intake of caloric food, coffee, diet soda/gum strictly not allowed during fasting period. Provide Age, gender, medication & clinical details .Lipemic & hameolysed sample should be avoided.
Specimen rejection criteria
Test run frequency
Every Day TIME - 09:00
Turn around time
Same Day
Performing locations
Department
- Protein Chemistry
CPT and Loinc codes
Package price
₹950
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